Caliendo grew up in Waukesha, Wisconsin, and attended University of Wisconsin–Milwaukee. Before graduating, he began performing stand-up at local comedy and nigh clubs, and ended up eventually taking a job as a master of ceremonies at a local comedy club. Caliendo is also well known for his spot on impressions, which are also part of his comedy routine.
He has performed stand-up on many series, including Premium Blend, Late Show with David Letterman, Late Late Show with Craig Kilborn, The View, The Late Late Show with Craig Ferguson and Late Night with Conan O'Brien. In 2001 he joined the cast of MADtv, but stopped working after its 2006-2007 season. Template:SpacerTemplate:WikipediaTemplate:Spacer
- Frank Caliendo on AllMovie
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- Frank Caliendo on Keek
- Frank Caliendo on Vine